KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK2
All Species:
13.03
Human Site:
S644
Identified Species:
26.06
UniProt:
Q9H0K1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0K1
NP_056006.1
926
103915
S644
P
Q
L
Q
D
L
A
S
S
C
P
Q
E
E
V
Chimpanzee
Pan troglodytes
XP_508750
883
99166
S601
P
Q
L
Q
D
L
A
S
S
C
P
Q
E
E
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546528
993
110460
G718
T
P
Q
L
Q
D
L
G
G
S
C
P
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFH6
931
104180
S644
P
Q
L
Q
D
L
S
S
S
C
P
Q
E
E
I
Rat
Rattus norvegicus
Q9R1U5
776
84890
A520
F
S
A
S
E
G
P
A
G
L
G
G
G
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511894
801
88312
A546
N
A
A
T
V
R
M
A
S
P
F
L
T
A
R
Chicken
Gallus gallus
Q9IA88
798
88848
L543
A
R
M
T
S
A
F
L
A
S
Q
S
D
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
T837
R
S
L
S
R
F
H
T
S
A
Y
E
Q
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
P1098
H
P
H
Q
H
P
H
P
H
P
Q
A
Y
G
L
Honey Bee
Apis mellifera
XP_397175
718
80391
S463
G
G
S
G
S
S
S
S
E
L
F
E
S
S
F
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
T879
Q
Q
M
S
R
S
A
T
T
N
S
A
N
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
P257
P
R
M
L
I
V
D
P
V
K
R
I
T
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
N.A.
84.7
N.A.
90.8
43.2
N.A.
45.2
45.4
N.A.
31.5
N.A.
29.6
37.4
23.8
N.A.
Protein Similarity:
100
95.3
N.A.
87.5
N.A.
94.4
56.7
N.A.
58.6
58.9
N.A.
45.2
N.A.
40
49.3
38.1
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
0
N.A.
6.6
0
N.A.
13.3
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
13.3
N.A.
13.3
26.6
N.A.
33.3
N.A.
13.3
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
0
0
9
25
17
9
9
0
17
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
25
9
0
0
0
0
% C
% Asp:
0
0
0
0
25
9
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
0
17
25
34
9
% E
% Phe:
9
0
0
0
0
9
9
0
0
0
17
0
0
0
9
% F
% Gly:
9
9
0
9
0
9
0
9
17
0
9
9
9
9
9
% G
% His:
9
0
9
0
9
0
17
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
34
17
0
25
9
9
0
17
0
9
0
17
9
% L
% Met:
0
0
25
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% N
% Pro:
34
17
0
0
0
9
9
17
0
17
25
9
0
0
17
% P
% Gln:
9
34
9
34
9
0
0
0
0
0
17
25
17
0
0
% Q
% Arg:
9
17
0
0
17
9
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
17
9
25
17
17
17
34
42
17
9
9
9
9
0
% S
% Thr:
9
0
0
17
0
0
0
17
9
0
0
0
17
0
9
% T
% Val:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _